Linking Metastatic Potential and Viscoelastic Properties of Breast Cancer Spheroids via Dynamic Compression and Relaxation in Microfluidics (Adv. Healthcare Mater. 6/2025)

Advanced Healthcare Materials, Volume 14, Issue 6, March 3, 2025.

Mar 4, 2025 - 09:59
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Linking Metastatic Potential and Viscoelastic Properties of Breast Cancer Spheroids via Dynamic Compression and Relaxation in Microfluidics (Adv. Healthcare Mater. 6/2025)

Viscoelastic Properties of Breast Cancer Spheroids

In article 2402715, Ankur D. Bordoloi, Pouyan E. Boukany, and co-workers link the viscoelastic properties of breast cancer spheroids to their metastatic potential. In a constricted microfluidic device, benign spheroids are found to be more elastic and viscous than malignant ones, with differences in their relaxation times, morphology, and cytoskeletal organization.