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Researchers find key to treating painful dry mouth disorder
A significant discovery has identified a missing "gatekeeper" protein as the root cause of dry mouth in Sjögren's syndrome - a finding that could change the way the disease is treated. Researchers pinpointed tricellulin, a protein that helps seal the junctions between saliva gland cells, as the key factor. When inflammation damages tricellulin, saliva production stops and harmful substances leak through.
A significant discovery has identified a missing "gatekeeper" protein as the root cause of dry mouth in Sjögren's syndrome - a finding that could change the way the disease is treated. Researchers pinpointed tricellulin, a protein that helps seal the junctions between saliva gland cells, as the key factor. When inflammation damages tricellulin, saliva production stops and harmful substances leak through.
