PLOS Biology

The G protein modifier KCTD5 tunes the decoding of neuromodulatory signals necessary for motor function in striatal neurons

The G protein modifier KCTD5 tunes the decoding of neur...

Apr 15, 2025 0

by Douglas C. Sloan, Yini Liao, Forest Ray, Brian S. Muntean G proteins (Gα and...

Mapping the ultrastructural topology of the corynebacterial cell surface

Mapping the ultrastructural topology of the corynebacte...

Apr 15, 2025 0

by Buse Isbilir, Anna Yeates, Vikram Alva, Tanmay A. M. Bharat Corynebacterium ...

Staphylococcal toxin PVL ruptures model membranes under acidic conditions through interactions with cardiolipin and phosphatidic acid

Staphylococcal toxin PVL ruptures model membranes under...

Apr 15, 2025 0

by Seong H. Chow, Yusun Jeon, Pankaj Deo, Amy T. Y. Yeung, Christine Hale, Sushm...

How did vocal communication come to dominate human language? A view from the womb

How did vocal communication come to dominate human lang...

Apr 15, 2025 0

by Alexis Hervais-Adelman, Simon W. Townsend Whether human language evolved via...

Transcriptomic atlas throughout <i>Coccidioides</i> development reveals key phase-enriched transcripts of this important fungal pathogen

Transcriptomic atlas throughout <i>Coccidioides</i> dev...

Apr 15, 2025 0

by Christina M. Homer, Mark Voorhies, Keith Walcott, Elena Ochoa, Anita Sil Coc...

Expanding the bat toolbox: <i>Carollia perspicillata</i> bat cell lines and reagents enable the characterization of viral susceptibility and innate immune responses

Expanding the bat toolbox: <i>Carollia perspicillata</i...

Apr 15, 2025 0

by Victoria Gonzalez, Cierra Word, Nahomi Guerra-Pilaquinga, Mitra Mazinani, Ste...

Applications and status of gene drive in plants

Applications and status of gene drive in plants

Apr 15, 2025 0

by Bruce A. Hay Gene drive can modify or suppress plant populations, offering s...

Monocyte-secreted Wnt reduces the efficiency of central nervous system remyelination

Monocyte-secreted Wnt reduces the efficiency of central...

Apr 15, 2025 0

by Bianca M. Hill, Rebecca K. Holloway, Lindsey H. Forbes, Claire L. Davies, Jon...

Structures of G-protein coupled receptor HCAR1 in complex with Gi1 protein reveal the mechanistic basis for ligand recognition and agonist selectivity

Structures of G-protein coupled receptor HCAR1 in compl...

Apr 15, 2025 0

by Xin Pan, Fang Ye, Peiruo Ning, Yiping Yu, Zhiyi Zhang, Jingxuan Wang, Geng Ch...

Liver gene expression and its rewiring in hepatic steatosis are controlled by PI3Kα-dependent hepatocyte signaling

Liver gene expression and its rewiring in hepatic steat...

Apr 14, 2025 0

by Marion Régnier, Arnaud Polizzi, Tiffany Fougeray, Anne Fougerat, Prunelle Per...

Vps34 puts the ‘e’ in eTreg cells

Vps34 puts the ‘e’ in eTreg cells

Apr 14, 2025 0

by Ruchi Saxena, You-Wen He Regulatory T cells (Tregs) exist in distinct subset...

One-for-one or one-for-all? Considerations for filovirus vaccine development

One-for-one or one-for-all? Considerations for filoviru...

Apr 14, 2025 0

by Andrea Marzi Filoviruses continue to re-emerge in Africa, causing localized ...

Hedgehog-stimulated phosphorylation at multiple sites activates Ci by altering Ci–Ci interfaces without full Suppressor of Fused dissociation

Hedgehog-stimulated phosphorylation at multiple sites a...

Apr 11, 2025 0

by Hoyon Kim, Jamie C. Little, Jiashen Li, Bryna Patel, Daniel Kalderon Hedgeho...

Vps34-orchestrated lipid signaling processes regulate the transitional heterogeneity and functional adaptation of effector regulatory T cells

Vps34-orchestrated lipid signaling processes regulate t...

Apr 11, 2025 0

by Erienne G. Norton, Nicole M. Chapman, Hao Shi, Xiaoxi Meng, Hongling Huang, A...

Interferon regulatory factor 4 mediates nonenzymatic IRE1 dependency in multiple myeloma cells

Interferon regulatory factor 4 mediates nonenzymatic IR...

Apr 11, 2025 0

by Ioanna Oikonomidi, Vasumathi Kameswaran, Victoria C. Pham, Iratxe Zuazo-Gazte...

Phase separation of the PRPP amidotransferase into dynamic condensates promotes de novo purine synthesis in yeast

Phase separation of the PRPP amidotransferase into dyna...

Apr 10, 2025 0

by Masak Takaine, Rikuri Morita, Yuto Yoshinari, Takashi Nishimura De novo puri...

MSP-tracker: A versatile vesicle tracking software tool used to reveal the spatial control of polarized secretion in <i>Drosophila</i> epithelial cells

MSP-tracker: A versatile vesicle tracking software tool...

Apr 10, 2025 0

by Jennifer H. Richens, Mariia Dmitrieva, Helen L. Zenner, Nadine Muschalik, Ric...

Top-down and bottom-up interactions rely on nested brain oscillations to shape rhythmic visual attention sampling

Top-down and bottom-up interactions rely on nested brai...

Apr 10, 2025 0

by Jelena Trajkovic, Domenica Veniero, Simon Hanslmayr, Satu Palva, Gabriela Cru...

Modulation of NMDA receptor signaling and zinc chelation prevent seizure-like events in a zebrafish model of SLC13A5 epilepsy

Modulation of NMDA receptor signaling and zinc chelatio...

Apr 10, 2025 0

by Deepika Dogra, Van Anh Phan, Sinan Zhang, Cezar Gavrilovici, Nadia DiMarzo, A...

Reanalysis of cryo-EM data reveals ALK-cytokine assemblies with both 2:1 and 2:2 stoichiometries

Reanalysis of cryo-EM data reveals ALK-cytokine assembl...

Apr 10, 2025 0

by Jan Felix, Steven De Munck, J. Fernando Bazan, Savvas N. Savvides Activation...

A nonenzymatic dependency on inositol-requiring enzyme 1 controls cancer cell cycle progression and tumor growth

A nonenzymatic dependency on inositol-requiring enzyme ...

Apr 10, 2025 0

by Iratxe Zuazo-Gaztelu, David Lawrence, Ioanna Oikonomidi, Scot Marsters, Ximo ...

Purkinje cells of the cerebellum control deceleration of tongue movements

Purkinje cells of the cerebellum control deceleration o...

Apr 10, 2025 0

by Paul Hage, Mohammad Amin Fakharian, Alden M. Shoup, Jay S. Pi, Ehsan Sedaghat...

TMED9 coordinates the clearance of misfolded GPI-anchored proteins out of the ER and into the Golgi

TMED9 coordinates the clearance of misfolded GPI-anchor...

Apr 9, 2025 0

by Elsa Ronzier, Prasanna Satpute-Krishnan The p24-family member, TMED9, has re...

Extreme diversity of phage amplification rates and phage–antibiotic interactions revealed by PHORCE

Extreme diversity of phage amplification rates and phag...

Apr 8, 2025 0

by Yuval Mulla, Janina Müller, Denny Trimcev, Tobias Bollenbach Growth rate pla...

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