Vps34 puts the ‘e’ in eTreg cells

by Ruchi Saxena, You-Wen He Regulatory T cells (Tregs) exist in distinct subsets, but key regulators of their heterogeneity remain unclear. A recent PLOS Biology study shows that the class III PI3K Vps34 acts as a master orchestrator, driving effector Treg generation and maintenance.

Apr 14, 2025 - 18:35
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Vps34 puts the ‘e’ in eTreg cells

by Ruchi Saxena, You-Wen He Regulatory T cells (Tregs) exist in distinct subsets, but key regulators of their heterogeneity remain unclear. A recent PLOS Biology study shows that the class III PI3K Vps34 acts as a master orchestrator, driving effector Treg generation and maintenance.