Reconstitution of SPO11-dependent double-strand break formation
Nature, Published online: 19 February 2025; doi:10.1038/s41586-025-08601-2Reconstitution of recombinantly expressed SPO11–TOP6BL complex recapitulates its DNA cleavage function and together with structural modelling and biochemical experiments, provides insights into the regulation and mechanism of SPO11 activity.
Nature, Published online: 19 February 2025; doi:10.1038/s41586-025-08601-2Reconstitution of recombinantly expressed SPO11–TOP6BL complex recapitulates its DNA cleavage function and together with structural modelling and biochemical experiments, provides insights into the regulation and mechanism of SPO11 activity.
