[Comment] Antenatal multiple micronutrient supplements: time for alignment to support country action

In 2020, WHO published guidance on the use of multiple micronutrient supplements (MMS) for pregnant women, which usually provide up to 15 vitamins and minerals in tablet or capsule form.1 In the 2020 update to the 2016 guidance,2 WHO issued a context-specific recommendation: “Antenatal multiple micronutrient supplements that include iron and folic acid are recommended in the context of rigorous research.”2 The evidence that informed this recommendation indicated that, compared with standard of care (iron and folic acid [IFA] supplementation), MMS reduced the prevalence of low birthweight but had little to no impact on other maternal and neonatal outcomes.

Mar 12, 2025 - 00:36
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In 2020, WHO published guidance on the use of multiple micronutrient supplements (MMS) for pregnant women, which usually provide up to 15 vitamins and minerals in tablet or capsule form.1 In the 2020 update to the 2016 guidance,2 WHO issued a context-specific recommendation: “Antenatal multiple micronutrient supplements that include iron and folic acid are recommended in the context of rigorous research.”2 The evidence that informed this recommendation indicated that, compared with standard of care (iron and folic acid [IFA] supplementation), MMS reduced the prevalence of low birthweight but had little to no impact on other maternal and neonatal outcomes.