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Zebrafish sperm outsource activation to eggs’ protease-activated receptors
by Rafael A. Fissore, Emily M. Lopes, Francesca Carpentiero The calcium surge that starts embryogenesis varies across species and is elusive in many. A new study in PLOS Biology shows that zebrafish eggs self-activate, initiating a protease-activated receptor calcium wave and uncovering a novel pathway in egg activation. The calcium surge that starts embryogenesis varies across species. A new study in PLOS Biology presents a novel mechanism of egg activation in zebrafish, wherein protease-activated receptors mediate a calcium signal that initiates egg activation before sperm entry.
by Rafael A. Fissore, Emily M. Lopes, Francesca Carpentiero The calcium surge that starts embryogenesis varies across species and is elusive in many. A new study in PLOS Biology shows that zebrafish eggs self-activate, initiating a protease-activated receptor calcium wave and uncovering a novel pathway in egg activation. The calcium surge that starts embryogenesis varies across species. A new study in PLOS Biology presents a novel mechanism of egg activation in zebrafish, wherein protease-activated receptors mediate a calcium signal that initiates egg activation before sperm entry.
