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Structure of mitochondrial pyruvate carrier and its inhibition mechanism
Nature, Published online: 05 March 2025; doi:10.1038/s41586-025-08667-yStructural findings define the architecture of the mitochondrial pyruvate carrier, delineate its substrate-binding site and translocation pathway, and reveal its major conformational states, providing the molecular basis for understanding its function and inhibition.
Nature, Published online: 05 March 2025; doi:10.1038/s41586-025-08667-yStructural findings define the architecture of the mitochondrial pyruvate carrier, delineate its substrate-binding site and translocation pathway, and reveal its major conformational states, providing the molecular basis for understanding its function and inhibition.
