STAT+: Gilead says its therapy delayed growth of tumors in aggressive form of breast cancer

Gilead Sciences said a combination of its cancer drug Trodelvy and Merck’s Keytruda delayed the growth of tumors in women with a less common, but aggressive form of breast cancer.

Apr 21, 2025 - 13:34
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STAT+: Gilead says its therapy delayed growth of tumors in aggressive form of breast cancer

Gilead Sciences said Monday that a combination of its cancer drug Trodelvy and Merck’s Keytruda delayed the growth of tumors in women with a less common, but aggressive form of breast cancer.

The results from a randomized Phase 3 study called ASCENT-04 could lead to a new treatment option for patients with newly diagnosed, metastatic, triple-negative breast cancer. Gilead could also benefit from a boost in Trodelvy sales at a time when it faces competition from a similar drug made by AstraZeneca and Daiichi Sankyo. 

In the study, the combination of Trodelvy and Keytruda demonstrated a “clinically meaningful” improvement in progression-free survival compared to Keytruda plus chemotherapy — achieving the study’s primary efficacy goal, Gilead said. 

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