Sodium Butyrate‐Loaded Microspheres With Enhanced Bioavailability for Targeted Treatment of Intestinal Barrier Injury (Adv. Healthcare Mater. 9/2025)
Advanced Healthcare Materials, Volume 14, Issue 9, April 4, 2025.

Butyrate-Loaded Microsphere
The cover image of article 2402773 by Jiulong Zhao, Zhaoshen Li, Shige Wang, and co-workers illustrates the therapeutic process of chitosan-protocatechuic aldehyde/calcium alginate/sodium butyrate (CPC/SB) microspheres in repairing intestinal barrier damage. Upon reaching inflamed intestinal villi, the spherical microspheres degrade to release sodium butyrate, which promotes healing, potentially by modulating the gut microbiota.