Neuronal receptors at body temperature reveal their gating mechanics

Nature, Published online: 26 March 2025; doi:10.1038/d41586-025-00865-yMost communication between neurons is mediated by the neurotransmitter glutamate. The finding that temperature influences how glutamate binds to neuronal receptor proteins to initiate signal transduction reveals the mechanics of one of the brain’s most important processes.

Mar 26, 2025 - 17:26
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Neuronal receptors at body temperature reveal their gating mechanics

Nature, Published online: 26 March 2025; doi:10.1038/d41586-025-00865-yMost communication between neurons is mediated by the neurotransmitter glutamate. The finding that temperature influences how glutamate binds to neuronal receptor proteins to initiate signal transduction reveals the mechanics of one of the brain’s most important processes.