Multianalyte Nanopore Detection of Alzheimer's Disease Biomarkers: A Label‐Free Platform with Improved Sensitivity and Range (Adv. Healthcare Mater. 16/2025)
Advanced Healthcare Materials, Volume 14, Issue 16, 23 June, 2025.

Alzheimer's Biomarkers
In article 2405058, Yang Zhan, Liang Wang, and co-workers describe recent advances in multianalyte nanopore detection of Alzheimer's biomarkers: a label-free platform with improved sensitivity and range. The image shows a little boy wearing a headlight, holding a net filled with tadpoles at dawn—a metaphor for how nanopore technology can detect and distinguish various Alzheimer's disease-related pathological proteins in bodily fluids during early stages. The mountain peaks in the background represent the current blockade amplitudes generated as different protein biomarkers pass through the nanopore.