Human assembloid model of the ascending neural sensory pathway

Nature, Published online: 09 April 2025; doi:10.1038/s41586-025-08808-3A human ascending somatosensory assembloid model was developed, which integrates multiple organoids to simulate the spinothalamic pathway, demonstrating functional connectivity and responsiveness to stimuli and revealing insights into pain-related genetic mutations.

Apr 9, 2025 - 16:36
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Human assembloid model of the ascending neural sensory pathway

Nature, Published online: 09 April 2025; doi:10.1038/s41586-025-08808-3A human ascending somatosensory assembloid model was developed, which integrates multiple organoids to simulate the spinothalamic pathway, demonstrating functional connectivity and responsiveness to stimuli and revealing insights into pain-related genetic mutations.