Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics (Adv. Healthcare Mater. 14/2025)

Antiviral Therapy

In article 2404818, Jin-Ho Choy and co-workers show the interaction of nanohybridized niclosamide with the Mpox virus, emphasizing its antiviral mechanisms. At the center, a disrupted viral structure is depicted, surrounded by a dynamic burst of molecular interactions. The nanohybrid drug carriers, represented as golden spherical nanoparticles, actively engage with the viral surface, releasing niclosamide molecules to inhibit viral replication and entry. The vibrant background, populated with red blood cells and immune components, highlights the biological environment where these therapeutic interventions take place. This artwork symbolizes the innovative fusion of nanomedicine and antiviral therapy, underscoring the potential of advanced material-based drug formulations in combating emerging viral threats.