Dual regulation of mitochondrial fusion by Parkin–PINK1 and OMA1
Nature, Published online: 19 February 2025; doi:10.1038/s41586-025-08590-2We find that, in mice, although the individual loss of Parkin or OMA1 does not affect mitochondrial integrity, their combined loss results in small body size, low locomotor activity, premature death, mitochondrial abnormalities and innate immune responses.
Nature, Published online: 19 February 2025; doi:10.1038/s41586-025-08590-2We find that, in mice, although the individual loss of Parkin or OMA1 does not affect mitochondrial integrity, their combined loss results in small body size, low locomotor activity, premature death, mitochondrial abnormalities and innate immune responses.
