[Comment] Fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting: please mind the gap

Early studies showed that coronary artery bypass grafting (CABG) was superior to percutaneous coronary intervention (PCI) in patients with three-vessel coronary artery disease for survival and event-free survival.1 Since these trials, there have been several advancements in medical therapy, PCI, and CABG. Determining whether a coronary stenosis is flow limiting by visual estimation alone can be subjective; PCI guided by fractional flow reserve (FFR), an objective functional measure of flow-limiting stenoses, has been shown to improve outcomes compared with PCI without FFR.