Statins for Primary Prevention of Cardiovascular Disease—Reply

In Reply Development of a new cardiovascular risk equation has prompted reconsideration of the appropriate thresholds at which to recommend preventive therapy. In response, Dr Demasi and colleagues argue that lowering the risk threshold for statins would increase adverse effects, such as myalgias, but not help patients live longer or better.

Mar 11, 2025 - 16:44
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In Reply Development of a new cardiovascular risk equation has prompted reconsideration of the appropriate thresholds at which to recommend preventive therapy. In response, Dr Demasi and colleagues argue that lowering the risk threshold for statins would increase adverse effects, such as myalgias, but not help patients live longer or better.