Personalized Patient Data and Behavioral Nudges for Medication Adherence—Reply

In Reply We thank Dr Pei and Dr Yuan and colleagues for interest in our study. We conducted a patient-level rather than a cluster-level randomized study because our intervention did not require specialized staff to deliver the intervention and the intervention utilizing text messages was delivered directly to patients. Intervention contamination could have occurred if patients in the intervention group communicated with those in the usual care group about the text messages and changed their medication refill behavior as a result. This scenario is possible, but the likelihood seems low.

May 13, 2025 - 16:46
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In Reply We thank Dr Pei and Dr Yuan and colleagues for interest in our study. We conducted a patient-level rather than a cluster-level randomized study because our intervention did not require specialized staff to deliver the intervention and the intervention utilizing text messages was delivered directly to patients. Intervention contamination could have occurred if patients in the intervention group communicated with those in the usual care group about the text messages and changed their medication refill behavior as a result. This scenario is possible, but the likelihood seems low.