Effective Hydrogel Vascular Patch Dual‐Loaded with Cycloastragenol Nanostructured Lipid Carriers and Doxycycline for Repairing Extravascular Injury in Abdominal Aortic Aneurysm (Adv. Healthcare Mater. 11/2025)

Advanced Healthcare Materials, Volume 14, Issue 11, April 25, 2025.

Apr 26, 2025 - 09:39
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Effective Hydrogel Vascular Patch Dual-Loaded with Cycloastragenol Nanostructured Lipid Carriers and Doxycycline for Repairing Extravascular Injury in Abdominal Aortic Aneurysm (Adv. Healthcare Mater. 11/2025)

Vascular Injury Repair

In the cover image of article 2402497 by Rong Qi and co-workers, the hydrogel patch is symbolized by auspicious clouds, reflecting its protective and therapeutic essence. The drugs incorporated in the patch–cycloastragenol nanostructured lipid carriers and doxycycline–are metaphorically represented as pearls held by a loong and a phoenix, two traditional Chinese auspicious creatures symbolizing auspicious and harmony. The ruptured riverbank signifies the damaged abdominal aorta caused by the aneurysm. The imagery illustrates how the hydrogel patch, laden with its dual-drug combination, works to repair and restore the injured blood vessel wall, mirroring the therapeutic process.