Regulation of PV interneuron plasticity by neuropeptide-encoding genes

Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08933-zIncreasing the activity of individual parvalbumin-expressing interneurons in the mouse brain modulates the number and strength of inhibitory parvalbumin synapses received by these cells through changes in the expression of the neuropeptide-encoding genes Vgf and Scg2.

Apr 30, 2025 - 17:00
 0
Regulation of PV interneuron plasticity by neuropeptide-encoding genes

Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08933-zIncreasing the activity of individual parvalbumin-expressing interneurons in the mouse brain modulates the number and strength of inhibitory parvalbumin synapses received by these cells through changes in the expression of the neuropeptide-encoding genes Vgf and Scg2.