Kupffer cell programming by maternal obesity triggers fatty liver disease

Nature, Published online: 18 June 2025; doi:10.1038/s41586-025-09190-wIn a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.

Jun 18, 2025 - 17:15
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Kupffer cell programming by maternal obesity triggers fatty liver disease

Nature, Published online: 18 June 2025; doi:10.1038/s41586-025-09190-wIn a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.