Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation

Nature, Published online: 18 June 2025; doi:10.1038/s41586-025-09120-wDysregulated CD4 T cells that recognize gut commensal antigens are able to infiltrate the central nervous systems and are re-stimulated by host proteins, resulting in neuroinflammation.

Jun 18, 2025 - 17:15
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Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation

Nature, Published online: 18 June 2025; doi:10.1038/s41586-025-09120-wDysregulated CD4 T cells that recognize gut commensal antigens are able to infiltrate the central nervous systems and are re-stimulated by host proteins, resulting in neuroinflammation.