Programmable control of spatial transcriptome in live cells and neurons

Nature, Published online: 21 May 2025; doi:10.1038/s41586-025-09020-zCRISPR-TO, a system for programmable control of spatial localization of cellular RNAs, is presented and enables functional investigation of endogenous RNA localization in diverse living cells.

May 21, 2025 - 17:05
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Programmable control of spatial transcriptome in live cells and neurons

Nature, Published online: 21 May 2025; doi:10.1038/s41586-025-09020-zCRISPR-TO, a system for programmable control of spatial localization of cellular RNAs, is presented and enables functional investigation of endogenous RNA localization in diverse living cells.