Clonal tracing with somatic epimutations reveals dynamics of blood ageing
Nature, Published online: 21 May 2025; doi:10.1038/s41586-025-09041-8The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone, an algorithm that enables single-cell lineage tracing through cellular differentiation at scale.
Nature, Published online: 21 May 2025; doi:10.1038/s41586-025-09041-8The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone, an algorithm that enables single-cell lineage tracing through cellular differentiation at scale.
