An Injectable Multifunctional Nanosweeper Eliminates Cardiac Mitochondrial DNA to Reduce Inflammation (Adv. Healthcare Mater. 11/2025)

Myocarditis

Nanosweeper, acting as a scavenger, arrives at the focal site of myocarditis through the navigation of heart-targeted peptides and starts to perform the task of mitochondrial DNA clearance. At the same time, STING inhibitors are held in hand to synergistic inhibit the STING pathway, inhibit the inflammatory storm and improve myocarditis. More details can be found in article 2404068 by Xiumeng Hua, Tao An, Jiangping Song, and co-workers.