Harnessing generative AI to expand the mitochondrial targeting toolkit

The mitochondrion, often referred to as the powerhouse of the cell, plays critical roles in cellular function, making it a prime organelle to target for fundamental studies, metabolic engineering, and disease therapies. With only a limited number of existing mitochondrial targeting sequences, a new study from the Carl R. Woese Institute for Genomic Biology demonstrates the utility of generative artificial intelligence for designing new ones.

May 10, 2025 - 21:04
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The mitochondrion, often referred to as the powerhouse of the cell, plays critical roles in cellular function, making it a prime organelle to target for fundamental studies, metabolic engineering, and disease therapies. With only a limited number of existing mitochondrial targeting sequences, a new study from the Carl R. Woese Institute for Genomic Biology demonstrates the utility of generative artificial intelligence for designing new ones.