Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor
Nature, Published online: 21 May 2025; doi:10.1038/s41586-025-09024-9Different phosphorylation patterns created by GRK2 and GRK5 on the C-terminal tail of ACKR3 lead to distinct structural arrangements and dynamics of G-protein-coupled receptor–arrestin complexes, potentially explaining diverse cellular outcomes.
Nature, Published online: 21 May 2025; doi:10.1038/s41586-025-09024-9Different phosphorylation patterns created by GRK2 and GRK5 on the C-terminal tail of ACKR3 lead to distinct structural arrangements and dynamics of G-protein-coupled receptor–arrestin complexes, potentially explaining diverse cellular outcomes.
