Celebrities Who Admit Using Ozempic For Weight Loss

Celebrities from Demi Moore to Oprah are turning to Ozempic and other GLP-1 drugs to shed pounds fast, ushering in a new era of weight loss. The post Celebrities Who Admit Using Ozempic For Weight Loss appeared first on LUXUO.

May 21, 2025 - 08:45
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Celebrities Who Admit Using Ozempic For Weight Loss
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The number of celebrities who admit to using Ozempic (semaglutide) for weight loss is growing. This year’s Golden Globes caused many commentators to speculate who was using the medication and the effects that it was having. 

Semaglutide is the generic name for a compound shown to increase the activation of the body’s GLP-1 receptors, little organelles that tell the brain that the stomach is full. Western diets full of sugary drinks, processed food, and junk aren’t good at activating these, causing people to consume more calories than they need, but medications like Ozempic do this automatically, reducing the risk of excessive calorie consumption. 

Originally, these drugs were meant for people with diabetes to help control hunger and weight gain. However, they proved so effective against obesity, the FDA and other medical organizations now approve them for weight loss or “weight management,” depending on how people want to read the label. 

The incredible and unreasonable effectiveness of these drugs first emerged in 2022. Stories broke of people losing up to 20 percent of their body weight on average from next-generation GLP-1 activators, which broke the record of previous-generation drugs that managed between 5 percent and 10 percent, adding even more excitement. 

Naturally, celebrities were among the first to jump on board with the idea of using semaglutide for weight loss. Numerous famous individuals in the music, movie, and sports world suddenly appeared to slim down, crediting their successes to their doctors or “pills.” 

After this early set of stories, the news gained momentum, and it became clear that semaglutide was a sort of miracle drug, similar to antibiotics. Scientists had finally figured out a way to help people lose weight sustainably, potentially dealing with one of the most significant issues in medicine–the negative health effects of obesity. 

Minimal is a wellness brand that offers semaglutide in a compounded form (often with added vitamins to assist the weight loss process). It has seen business balloon as the word has spread. 

“The idea that people could take a pill and lose weight was science fiction in 2020, but in 2025 it is normal,” the company says. “The speed of change is nothing less than remarkable, underscoring the incredible impact the drug is having on communities and people’s lives.” 

So, which celebrities are rumored to be using Ozempic and other forms of similar medications? 

Demi Moore tops the list of suspects. While she always kept a svelte frame thanks to her whole food diet, many observers believe she may have taken her figure efforts up a notch with Ozempic. Photos of her at the Golden Globes in January 2025 show her slimmed down compared to her regular appearance. 

Another candidate is Selena Gomez, the famous singer and champion of body positivity. This year, she appears to have lost significant weight, perhaps because of her ongoing battle with lupus, but also potentially because of her use of the drug. 

Besides these, many celebrities have admitted to using the drug. One of the first to come out of the woodwork was singer Kelly Clarkson who struggled with her weight for years. She said that her doctor pestered her for over two years to try the drug before she finally relented, allowing her to lose a significant percentage of her body mass in just a few months. Part of the reason for her finally taking the plunge was her bloodwork, which showed that she was on course for chronic conditions in mid-life, like heart disease, if she didn’t take immediate action. 

Whoopi Goldberg is another example of the effectiveness of a similar drug, called Monjaro, for fighting the bulge. She told reporters that she needed the medication because she was worried about the toll her lifestyle was taking on her health, believing that she carried that weight of “two people”.

After taking the shots, she says it has been good for her, and it accounts for most of the weight she’s lost over the years. 

Oprah is another star who has benefited from the new generation of prescription weight loss drugs. She was always in favor of a healthy lifestyle, but found it hard to keep her weight down sometimes, which is why she moved over to these medications. She found that they allowed her to stay and feel healthier overall. 

Rebel Wilson has also admitted to using weight-loss drugs, like semaglutide. For years, she was known as one of the most successful overweight female movie stars globally, but since taking semaglutide, she’s slimmed down considerably and no longer has the food cravings she once did. 

Previously, she had had a bottomless appetite for sweets, and no amount of willpower could really stop her from eating them. But today, the GLP-1 activation is taking the edge off that and reducing the amount she needs to eat in general. People originally thought that she’d lose her niche in the movie world as the fat, funny female lead. But so far, that hasn’t happened, and she’s been able to take on new films. 

Finally, Sharon and Kelly Osborne, the mother and daughter pair, also publicly disclosed that they used Ozempic. The drugs proved so effective that Sharon said that she’d lost too much weight on them, while Kelly loved the results that she had gotten. 

The list of celebrities using these medications is almost endless, and this article would be several thousand words long to go through all of them. But what is clear is that this technology works, and it isn’t a gimmick. 

“The fact that so many celebrities are using these weight loss drugs is a testament to their effectiveness,” explains Minimal. “Even many of the researchers working on these projects didn’t foresee how game-changing many of these compounds would be, like trizepide and semaglutide. They thought that they’d reduce appetite and curb weight gain, but only a few brave individuals dared to imagine weight losses in the region of 20% of total body mass.”

Of course, a healthy diet and lifestyle are still important. Scientists warn that semaglutide and similar medications are just that: medicines. They can’t substitute for everything else that makes a person healthy. 

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