Performance and Agreement of Coronary Heart Disease Polygenic Risk Scores—Reply
In Reply We appreciate Dr Shan’s thoughtful commentary on our study examining performance and agreement of coronary heart disease PRSs. The letter raises important points about methodology for evaluating coronary heart disease PRSs, as well as interpreting and acting on our findings that similarly performing scores provide discordant individual-level risk estimates.
In Reply We appreciate Dr Shan’s thoughtful commentary on our study examining performance and agreement of coronary heart disease PRSs. The letter raises important points about methodology for evaluating coronary heart disease PRSs, as well as interpreting and acting on our findings that similarly performing scores provide discordant individual-level risk estimates.
