The innate immune system: A double-edged sword

by Ditte S. Andersen, Julien Colombani Innate immunity serves as a crucial surveillance framework, but can be exploited to facilitate tumor progression. Two new PLOS Biology studies independently show how premalignant cells can exploit Toll-NF-κB signaling, in concert with oncogenic Ras, to enable unchecked growth

May 12, 2025 - 10:11
 0
The innate immune system: A double-edged sword

by Ditte S. Andersen, Julien Colombani Innate immunity serves as a crucial surveillance framework, but can be exploited to facilitate tumor progression. Two new PLOS Biology studies independently show how premalignant cells can exploit Toll-NF-κB signaling, in concert with oncogenic Ras, to enable unchecked growth