Chromatin loops are an ancestral hallmark of the animal regulatory genome

Nature, Published online: 07 May 2025; doi:10.1038/s41586-025-08960-wThe physical organization of the genome in non-bilaterian animals and their closest unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of genome architecture and spatial genome regulation emerged early in animal evolution.

May 7, 2025 - 16:42
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Chromatin loops are an ancestral hallmark of the animal regulatory genome

Nature, Published online: 07 May 2025; doi:10.1038/s41586-025-08960-wThe physical organization of the genome in non-bilaterian animals and their closest unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of genome architecture and spatial genome regulation emerged early in animal evolution.