Chromatin loops are an ancestral hallmark of the animal regulatory genome
Nature, Published online: 07 May 2025; doi:10.1038/s41586-025-08960-wThe physical organization of the genome in non-bilaterian animals and their closest unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of genome architecture and spatial genome regulation emerged early in animal evolution.

Nature, Published online: 07 May 2025; doi:10.1038/s41586-025-08960-wThe physical organization of the genome in non-bilaterian animals and their closest unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of genome architecture and spatial genome regulation emerged early in animal evolution.