Activation of lysosomal iron triggers ferroptosis in cancer
Nature, Published online: 07 May 2025; doi:10.1038/s41586-025-08974-4Some cancer cells exhibit high loads of reactive iron in lysosomes, and this feature is exploited by using fentomycin-1, a newly developed small molecule, to induce ferroptosis.
Nature, Published online: 07 May 2025; doi:10.1038/s41586-025-08974-4Some cancer cells exhibit high loads of reactive iron in lysosomes, and this feature is exploited by using fentomycin-1, a newly developed small molecule, to induce ferroptosis.
