Gene promoters are genomically encoded to facilitate histone exchange/incorporation

by Blaine Bartholomew Gene promoters are intrinsically hardwired not only to facilitate transcription preinitiation complex formation but also the release of paused RNA polymerase by H2A.Z. A new PLOS Biology study reveals poly (dA) tracts at promoters positively stimulate H2A.Z incorporation by the SWR complex in yeast. Gene promoter regions are intrinsically hardwired not only to facilitate transcription preinitiation complex formation, but also the release of paused RNA polymerase by H2A.Z. Ed Luk and colleagues reveal poly (dA) tracks at promoters positively stimulates the incorporation of H2A.Z by the SWR complex in Saccharomyces cerevisiae.

May 13, 2025 - 18:54
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Gene promoters are genomically encoded to facilitate histone exchange/incorporation

by Blaine Bartholomew Gene promoters are intrinsically hardwired not only to facilitate transcription preinitiation complex formation but also the release of paused RNA polymerase by H2A.Z. A new PLOS Biology study reveals poly (dA) tracts at promoters positively stimulate H2A.Z incorporation by the SWR complex in yeast. Gene promoter regions are intrinsically hardwired not only to facilitate transcription preinitiation complex formation, but also the release of paused RNA polymerase by H2A.Z. Ed Luk and colleagues reveal poly (dA) tracks at promoters positively stimulates the incorporation of H2A.Z by the SWR complex in Saccharomyces cerevisiae.